N-of-1-pathways MixEnrich: advancing precision medicine via
single-subject analysis in discovering dynamic changes of transcriptomes
Qike Lia-d,§,
A. Grant Schisslera-d,§,
Vincent Gardeuxa-c, Ikbel Achoura-c,
Colleen Kenosta-c, Haiquan Lia-c,*, Hao
Helen Zhangd,e,*, Yves A. Lussiera-d, f-g,*
aCenter for Biomedical Informatics and Biostatistics, The University of Arizona, Tucson, AZ, 85721, USA
bBio5 Institute,
The University of Arizona, Tucson, AZ, 85721, USA
cDepartment of Medicine,
The University of Arizona, Tucson, AZ, 85721, USA
dGraduate
Interdisciplinary Program in Statistics,
The University of Arizona, Tucson, AZ, 85721, USA
eDepartment of Mathematics,
The University of Arizona, Tucson, AZ, 85721, USA
fUniversity
of Arizona Cancer Center, The University of Arizona, Tucson, AZ, 85721, USA,
gInstitute
for Genomics and Systems Biology, The University of Chicago, IL 60637, USA
§These
authors contributed equally to the work
*To whom correspondence should be addressed
Supplementary materials:
readme.txt